Dichloromethane → N-[(2,4-dichlorophenyl)methyl]pyrrolidin-3-amine

HRID 1213664Notes

Reaction equation

HRID 1213664 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([NH:13][CH2:14][c:15]2[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:11][CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:30][CH2:31][Cl:32].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH:8]1[CH2:9][CH:10]([NH:13][CH2:14][c:15]2[c:16]([Cl:22])[cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:11][CH2:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 66854616Tert-butyl 3-[(2,4-dichlorophenyl)methylamino]pyrrolidine-1-carboxylate

Product 1

HCID 60137425N-[(2,4-dichlorophenyl)methyl]pyrrolidin-3-amine

Sources & evidence

ORD record
ord-5b815ed3068942699782fcac8881aac2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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