Hydrochloric Acid → Hydrochloric Acid

HRID 1213690Notes

Reaction equation

HRID 1213690 reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([O:34][CH3:35])[cH:12][c:13]2[c:14]([NH:20][c:21]3[c:22]([F:33])[cH:23][c:24]([CH3:32])[c:25]([O:27][C:28]([O:29][CH3:30])=[O:31])[cH:26]3)[n:15][cH:16][n:17][c:18]2[cH:19]1.[CH3:40][OH:41].[ClH:1].[ClH:39].[Na+:37].[OH-:36].[OH2:38]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([O:34][CH3:35])[cH:12][c:13]2[c:14]([NH:20][c:21]3[c:22]([F:33])[cH:23][c:24]([CH3:32])[c:25]([OH:27])[cH:26]3)[n:15][cH:16][n:17][c:18]2[cH:19]1.[ClH:1]

Participants

8

Reactant 6

HCID 313Hydrochloric Acid2×HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 226249317-Benzyloxy-4-(2-fluoro-5-methoxycarbonyloxy-4-methylanilino)-6-methoxyquinazoline

Product 2

HCID 313Hydrochloric AcidHCID 158860424-Fluoro-5-[(6-methoxy-7-phenylmethoxyquinazolin-4-yl)amino]-2-methylphenol

Sources & evidence

ORD record
ord-2d4c46491e714adab32b574afa4b2f04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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