Dichloromethane → 5-chloro-4-[5-chloro-6-(1,1,1-trifluoropropan-2-yloxy)pyridin-3-yl]oxy-2-fluoro-N-methylsulfonylbenzamide

HRID 1213794Notes

Reaction equation

HRID 1213794 reaction equation
[CH3:60][S:61](=[O:62])(=[O:63])[NH2:64].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[Cl:10][c:11]1[c:12]([O:21][c:22]2[cH:23][n:24][c:25]([O:29][CH:30]([C:31]([F:32])([F:33])[F:34])[CH3:35])[c:26]([Cl:28])[cH:27]2)[cH:13][c:14]([F:20])[c:15]([C:16](=[O:17])[OH:18])[cH:19]1.[Cl:65][CH2:66][Cl:67].[F:36][P-:37]([F:38])([F:39])([F:40])([F:41])[F:42].[n:43]1([O:44][C:45]([N:46]([CH3:47])[CH3:48])=[N+:49]([CH3:50])[CH3:51])[c:52]2[n:53][cH:54][cH:55][cH:56][c:57]2[n:58][n:59]1>>[Cl:10][c:11]1[c:12]([O:21][c:22]2[cH:23][n:24][c:25]([O:29][CH:30]([C:31]([F:32])([F:33])[F:34])[CH3:35])[c:26]([Cl:28])[cH:27]2)[cH:13][c:14]([F:20])[c:15]([C:16](=[O:17])[NH:64][S:61]([CH3:60])(=[O:62])=[O:63])[cH:19]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 72879MethanesulfonamideHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 766712685-Chloro-4-[[5-chloro-6-(1,1,1-trifluoropropan-2-yloxy)-3-pyridinyl]oxy]-2-fluorobenzoic acid

Product 1

HCID 566442135-chloro-4-[5-chloro-6-(1,1,1-trifluoropropan-2-yloxy)pyridin-3-yl]oxy-2-fluoro-N-methylsulfonylbenzamide

Sources & evidence

ORD record
ord-bc590585040d4c449d0453c2f053dec9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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