Hydrogen Bromide → Hydrogen Bromide

HRID 1214642Notes

Reaction equation

HRID 1214642 reaction equation
[BrH:31].[CH2:59]([Cl:60])[Cl:61].[CH:44]1([N:45]=[C:46]=[N:47][CH:48]2[CH2:49][CH2:50][CH2:51][CH2:52][CH2:53]2)[CH2:54][CH2:55][CH2:56][CH2:57][CH2:58]1.[O:32]1[CH2:33][CH2:34][N:35]([CH2:38][CH2:39][CH2:40][C:41](=[O:42])[OH:43])[CH2:36][CH2:37]1.[OH:1][c:2]1[c:3]([CH3:30])[c:4]([C:18]([CH2:19][CH2:20][CH3:21])([CH3:22])[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[c:5]([CH3:17])[c:6]2[c:11]1[CH:10]1[CH:9]([CH:8]([CH3:16])[O:7]2)[CH2:15][CH2:14][CH:13]=[CH:12]1>>[BrH:31].[O:1]([c:2]1[c:3]([CH3:30])[c:4]([C:18]([CH2:19][CH2:20][CH3:21])([CH3:22])[c:23]2[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]2)[c:5]([CH3:17])[c:6]2[c:11]1[CH:10]1[CH:9]([CH:8]([CH3:16])[O:7]2)[CH2:15][CH2:14][CH:13]=[CH:12]1)[C:41]([CH2:40][CH2:39][CH2:38][N:35]1[CH2:34][CH2:33][O:32][CH2:37][CH2:36]1)=[O:42]

Participants

7

Reactant 5

HCID 260Hydrogen BromideHCID 6344DichloromethaneHCID 10868DicyclohexylcarbodiimideHCID 798724-Morpholinebutanoic acidHCID 681217831-Hydroxy-3-(4-fluorophenyl-1-methylbutyl)-trimethyl-6a,7,8,10a-tetrahydrodibenzo[b,d] pyran

Product 2

HCID 260Hydrogen BromideHCID 86734784[3-[2-(4-fluorophenyl)pentan-2-yl]-2,4,6-trimethyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-yl] 4-morpholin-4-ylbutanoate

Sources & evidence

ORD record
ord-7f249149669848709145121bc0986bf3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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