Dimethylformamide → 1,1-Dimethylethyl 4-[(2-chloro-6,7-dihydro-5H-cyclopentapyrimidin-4-yl)amino]-1-piperidinecarboxylate

HRID 1214864Notes

Reaction equation

HRID 1214864 reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][CH:22]([NH2:25])[CH2:23][CH2:24]1.[Cl:1][c:2]1[n:3][c:4]2[c:5]([c:6]([Cl:8])[n:7]1)[CH2:9][CH2:10][CH2:11]2.[O:26]=[CH:27][N:28]([CH3:29])[CH3:30]>>[Cl:1][c:2]1[n:3][c:4]2[c:5]([c:6]([NH:25][CH:22]3[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23]3)[n:7]1)[CH2:9][CH2:10][CH2:11]2

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 2313312,4-dichloro-5H,6H,7H-cyclopenta(d)pyrimidineHCID 12682914-Amino-1-Boc-piperidine

Product 1

HCID 863463121,1-Dimethylethyl 4-[(2-chloro-6,7-dihydro-5H-cyclopentapyrimidin-4-yl)amino]-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-1ef9cd41b9f644f9859a2907aed77fb5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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