Ammonium → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-{[(2-hydroxy-acetyl)-methoxy-amino]-methyl}-N-(2-hydroxy-ethoxy)-benzamide

HRID 1214926Notes

Reaction equation

HRID 1214926 reaction equation
[CH3:1][O:2][C:3](=[O:4])[CH2:35][C:5]([N:6]([O:7][CH3:8])[CH2:9][c:10]1[c:11]([F:33])[c:12]([F:32])[c:13]([NH:23][c:24]2[c:25]([F:31])[cH:26][c:27]([I:30])[cH:28][cH:29]2)[c:14]([C:16]([NH:17][O:18][CH2:19][CH2:20][OH:21])=[O:22])[cH:15]1)=[O:34].[CH3:36][O-:37].[CH3:39][OH:40].[Cl-:41].[NH4+:42].[Na+:38]>>[C:5]([N:6]([O:7][CH3:8])[CH2:9][c:10]1[c:11]([F:33])[c:12]([F:32])[c:13]([NH:23][c:24]2[c:25]([F:31])[cH:26][c:27]([I:30])[cH:28][cH:29]2)[c:14]([C:16]([NH:17][O:18][CH2:19][CH2:20][OH:21])=[O:22])[cH:15]1)(=[O:34])[CH2:36][OH:37]

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 887MethanolHCID 923Sodium ionHCID 3826051MethoxideHCID 86634365{[2,3-Difluoro-4-(2-fluoro-4-iodo-phenylamino)-5-(2-hydroxy-ethoxycarbamoyl)-benzyl]-methoxy-carbamoyl}acetic acid methyl ester

Product 1

HCID 117068243,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-{[(2-hydroxy-acetyl)-methoxy-amino]-methyl}-N-(2-hydroxy-ethoxy)-benzamide

Sources & evidence

ORD record
ord-9d9bc3b3a74f4453a66046ea029adfc3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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