Imidazole → 5-(((tert-Butyldimethylsilyl)oxy)methyl)pyrrolidin-2-one
Reaction equation
[C:14]([CH3:15])([CH3:16])([CH3:17])[Si:18]([CH3:19])([CH3:20])[Cl:21].[CH3:22][N:23]([CH3:24])[c:25]1[cH:26][cH:27][n:28][cH:29][cH:30]1.[Cl:31][CH2:32][Cl:33].[OH:6][CH2:7][CH:8]1[CH2:9][CH2:10][C:11](=[O:13])[NH:12]1.[nH:1]1[cH:2][cH:3][n:4][cH:5]1>>[O:6]([CH2:7][CH:8]1[CH2:9][CH2:10][C:11](=[O:13])[NH:12]1)[Si:18]([C:14]([CH3:15])([CH3:16])[CH3:17])([CH3:19])[CH3:20]Participants
6
Sources & evidence
- ORD record
- ord-5a978c4fd5ab4586a3f5989abe790fa1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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