Dichloromethane → 8-acetyl-2-(1-aminoethyl)-3-(4-ethoxyphenyl)-6,7-dihydro-5H-pyrido[2,3-d]pyrimidin-4-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH3:9])[c:10]1[n:11](-[c:24]2[cH:25][cH:26][c:27]([O:30][CH2:31][CH3:32])[cH:28][cH:29]2)[c:12](=[O:23])[c:13]2[c:14]([n:15]1)[N:16]([C:20]([CH3:21])=[O:22])[CH2:17][CH2:18][CH2:19]2)([CH3:5])([CH3:6])[CH3:33].[Cl:34][CH2:35][Cl:36].[OH:37][C:38]([C:39]([F:40])([F:41])[F:42])=[O:43]>>[NH2:7][CH:8]([CH3:9])[c:10]1[n:11](-[c:24]2[cH:25][cH:26][c:27]([O:30][CH2:31][CH3:32])[cH:28][cH:29]2)[c:12](=[O:23])[c:13]2[c:14]([n:15]1)[N:16]([C:20]([CH3:21])=[O:22])[CH2:17][CH2:18][CH2:19]2Participants
4
Sources & evidence
- ORD record
- ord-a784b8b914a2400faf6da5b669955bc4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…