Dichloromethane → 2-Amino-1-[4-(3,4-dichlorophenoxy)-piperidine-1-yl]-3-methyl-butan-1-one
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([O:5][CH:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:13])[CH:14]([CH:15]([CH3:16])[CH3:17])[NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:10][CH2:11]2)[cH:26][cH:27][c:28]1[Cl:29].[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[Cl:1][c:2]1[cH:3][c:4]([O:5][CH:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:13])[CH:14]([CH:15]([CH3:16])[CH3:17])[NH2:18])[CH2:10][CH2:11]2)[cH:26][cH:27][c:28]1[Cl:29]Participants
4
Sources & evidence
- ORD record
- ord-49b87f86898c4c578989685238262dd3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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