Ethanol → 3-(5-Bromo-pyrimidin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:15][c:16]1[cH:17][n:18][c:19]([Cl:22])[n:20][cH:21]1.[CH3:32][CH2:33][OH:34].[CH:23]([N:24]([CH2:25][CH3:26])[CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31].[NH2:1][CH:2]1[CH2:3][N:4]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:5][CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][N:4]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:5][CH2:6][CH2:7]1)[c:19]1[n:18][cH:17][c:16]([Br:15])[cH:21][n:20]1Participants
5
Sources & evidence
- ORD record
- ord-5be575c73ea6465dab9ef6f96d9ea19a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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