Dichloromethane → Hexahydro-2H-isothiazolo[2,3-a]pyrazine 1,1-dioxide

HRID 1215902Notes

Reaction equation

HRID 1215902 reaction equation
[Cl:26][CH2:27][Cl:28].[F:19][C:20]([F:21])([F:22])[C:23]([OH:24])=[O:25].[S:1]1(=[O:17])(=[O:18])[CH2:2][CH2:3][CH:4]2[N:5]1[CH2:6][CH2:7][N:8]([C:10]([O:11][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:16])[CH2:9]2>>[S:1]1(=[O:17])(=[O:18])[CH2:2][CH2:3][CH:4]2[N:5]1[CH2:6][CH2:7][NH:8][CH2:9]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59215825tert-butyl 1,1-dioxo-hexahydro-2H-1lambda6-[1,2]thiazolo[2,3-a]piperazine-5-carboxylate

Product 1

HCID 59215775Hexahydro-2H-isothiazolo[2,3-a]pyrazine 1,1-dioxide

Sources & evidence

ORD record
ord-7d079cc9cd6842d9a56faf403018cc36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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