Hydrochloric Acid → N-[2,6-Dimethyl-4-(7-trifluoromethyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl]-3,3-dimethyl-butanamide
Reaction equation
[Br:50][c:51]1[cH:52][c:53]([CH3:66])[c:54]([NH:58][C:59]([CH2:60][C:61]([CH3:62])([CH3:63])[CH3:64])=[O:65])[c:55]([CH3:57])[cH:56]1.[CH3:29][C:30]([CH3:31])([O-:32])[CH3:33].[CH3:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1.[CH:1]1([P:2]([CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2-[c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]2[N:21]([CH3:22])[CH3:23])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1.[ClH:35].[F:36][C:37]([c:38]1[cH:39][cH:40][c:41]2[c:46]([cH:47]1)[CH2:45][NH:44][CH2:43][CH2:42]2)([F:48])[F:49].[K+:34]>>[F:36][C:37]([c:38]1[cH:39][cH:40][c:41]2[c:46]([cH:47]1)[CH2:45][N:44]([c:51]1[cH:52][c:53]([CH3:66])[c:54]([NH:58][C:59]([CH2:60][C:61]([CH3:62])([CH3:63])[CH3:64])=[O:65])[c:55]([CH3:57])[cH:56]1)[CH2:43][CH2:42]2)([F:48])[F:49]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-7d218916f54c47b1a92903ef9381fcff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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