Tetrahydrofuran → 6-Amino-2-N-Boc-1,2,3,4-tetrahydro-isoquinoline

HRID 1216081Notes

Reaction equation

HRID 1216081 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([N+:18]([O-:19])=[O:20])[cH:14][c:15]2[CH2:16][CH2:17]1.[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([NH2:18])[cH:14][c:15]2[CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 15491253tert-Butyl 6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate

Product 1

HCID 27563716-Amino-2-N-Boc-1,2,3,4-tetrahydro-isoquinoline

Sources & evidence

ORD record
ord-f8863ac2d0dc42689cbc439c8d908470
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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