Hydrochloric Acid → N-(5-(2-aminoimidazo[1,2-b]pyridazin-6-yl)-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide

HRID 1216246Notes

Reaction equation

HRID 1216246 reaction equation
[CH3:33][OH:34].[Cl:1][c:2]1[c:3]([NH:21][S:22](=[O:23])(=[O:24])[c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]2)[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]3[n:12]([n:13]2)[cH:14][c:15]([NH:17][C:18](=[O:19])[CH3:20])[n:16]3)[cH:6][n:7]1.[ClH:32]>>[Cl:1][c:2]1[c:3]([NH:21][S:22](=[O:23])(=[O:24])[c:25]2[cH:26][cH:27][c:28]([F:31])[cH:29][cH:30]2)[cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]3[n:12]([n:13]2)[cH:14][c:15]([NH2:17])[n:16]3)[cH:6][n:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 44124863N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)imidazo[1,2-b]pyridazin-2-yl)acetamide

Product 1

HCID 44125256N-(5-(2-aminoimidazo[1,2-b]pyridazin-6-yl)-2-chloropyridin-3-yl)-4-fluorobenzenesulfonamide

Sources & evidence

ORD record
ord-395e6f80141046428d6ddd7a6ea313ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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