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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1216365Generated: October 31, 2026

1,2-Dichloroethane → N1-(4-(2-(1-Ethyl-1H-imidazol-5-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-(2-fluorophenyl)malonamide

https://huagongshe.com/reaction/1216365

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylformamideHCID 6228—
Reactant1-HydroxybenzotriazoleHCID 75771—
Reactant2-[(2-Fluorophenyl)carbamoyl]acetic acidHCID 16481156—
Reactant4-(2-(1-Ethyl-1H-imidazol-5-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroanilineHCID 58790425—
ProductN1-(4-(2-(1-Ethyl-1H-imidazol-5-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-N3-(2-fluorophenyl)malonamideHCID 58790094—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-4ff54f385ab44a26849f93c29a7b276b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)