Dichloromethane → Trifluoroacetic acid

HRID 1216608Notes

Reaction equation

HRID 1216608 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[cH:14][c:15]2[CH2:16]1)([CH3:5])([CH3:6])[CH3:7].[Cl:32][CH2:33][Cl:34].[F:25][C:26]([C:27](=[O:28])[OH:29])([F:30])[F:31]>>[F:25][C:26]([C:27](=[O:28])[OH:29])([F:30])[F:31].[NH:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[cH:14][c:15]2[CH2:16]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 17986287N-t-Butoxycarbonyl-5-[(morpholin-4-yl)carbonyl]isoindoline

Product 2

HCID 6422Trifluoroacetic acidHCID 179862832,3-dihydro-1H-isoindol-5-yl(morpholin-4-yl)methanone

Sources & evidence

ORD record
ord-519c9d49c95740bf8578ea674d24b039
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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