Dichloromethane → Methyl 3-[2-(2,6-dichlorophenyl)quinolin-6-yl]alaninate

HRID 1217327Notes

Reaction equation

HRID 1217327 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][CH:9]([C:10](=[O:11])[O:12][CH3:13])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][c:20](-[c:25]3[c:26]([Cl:32])[cH:27][cH:28][cH:29][c:30]3[Cl:31])[n:21][c:22]2[cH:23][cH:24]1)([CH3:5])([CH3:6])[CH3:7].[Cl:40][CH2:41][Cl:42].[F:33][C:34]([F:35])([F:36])[C:37]([OH:38])=[O:39]>>[NH2:8][CH:9]([C:10](=[O:11])[O:12][CH3:13])[CH2:14][c:15]1[cH:16][c:17]2[cH:18][cH:19][c:20](-[c:25]3[c:26]([Cl:32])[cH:27][cH:28][cH:29][c:30]3[Cl:31])[n:21][c:22]2[cH:23][cH:24]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 11248518methyl N-(tert-butoxycarbonyl)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]alaninate

Product 1

HCID 24755559Methyl 3-[2-(2,6-dichlorophenyl)quinolin-6-yl]alaninate

Sources & evidence

ORD record
ord-f5fce2a146e6468da5114a1e9b3ae6de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…