反应详情

A mixture of citraconic anhydride (1.00 mL, 11.1 mmol) and 2-amino-5-bromopyridine (1.93 g, 11.2 mmol) in toluene (60 mL) was heated to reflux overnight. The solution was cooled down, filtered. The filtrate was concentrated in vacuo to give a solid (2.10 g, yield: 71%). MS 267 and 269 (M+H).

1. temperaturewas heated
2. temperatureto reflux overnight
3. temperatureThe solution was cooled down
4. filtrationfiltered
5. concentrationThe filtrate was concentrated in vacuo