Dimethylformamide → 4-[4-(3-Fluoro-4-methanesulfonyl-phenoxy)pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:36]([CH3:37])([CH3:38])([CH3:39])[O:40][C:41](=[O:42])[N:43]1[CH2:44][CH2:45][CH:46]([n:49]2[n:50][cH:51][c:52]3[c:53]2[n:54][cH:55][n:56][c:57]3[Cl:58])[CH2:47][CH2:48]1.[CH3:71][N:72]([CH3:73])[CH:74]=[O:75].[F:1][c:2]1[cH:3][c:4]([S:5]([CH3:6])(=[O:7])=[O:8])[cH:9][cH:10][c:11]1[O:12][c:13]1[n:14][cH:15][n:16][c:17]2[n:18]([CH:19]3[CH2:20][CH2:21][CH:22]([c:23]4[o:24][n:25][c:26]([CH:27]([CH3:28])[CH3:29])[n:30]4)[CH2:31][CH2:32]3)[n:33][cH:34][c:35]12.[F:59][c:60]1[cH:61][c:62]([OH:70])[cH:63][cH:64][c:65]1[S:66](=[O:67])(=[O:68])[CH3:69]>>[C:36]([CH3:37])([CH3:38])([CH3:39])[O:40][C:41](=[O:42])[N:43]1[CH2:44][CH2:45][CH:46]([n:49]2[n:50][cH:51][c:52]3[c:53]2[n:54][cH:55][n:56][c:57]3[O:70][c:62]2[cH:61][c:60]([F:59])[c:65]([S:66](=[O:67])(=[O:68])[CH3:69])[cH:64][cH:63]2)[CH2:47][CH2:48]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-65f83ae1660447a9a8c73320fbc08453
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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