Dichloromethane → 1-(2-Chloro-7-methylquinazolin-4-yl)pyrrolidin-3-amine
Reaction equation
[Cl:1][c:2]1[n:3][c:4]2[cH:5][c:6]([CH3:25])[cH:7][cH:8][c:9]2[c:10]([N:12]2[CH2:13][CH:14]([NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:15][CH2:16]2)[n:11]1.[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[Cl:1][c:2]1[n:3][c:4]2[cH:5][c:6]([CH3:25])[cH:7][cH:8][c:9]2[c:10]([N:12]2[CH2:13][CH:14]([NH2:17])[CH2:15][CH2:16]2)[n:11]1Participants
4
Sources & evidence
- ORD record
- ord-6068b628781a45c4b5068d01159d1bd3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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