Sodium ion → N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-5-fluoro-4-methylbenzamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6]([CH3:9])[c:7]1=[O:8])[n:10](-[c:13]1[c:14]([F:20])[cH:15][cH:16][cH:17][c:18]1[F:19])[n:11][cH:12]2.[C:50](=[O:51])([O-:52])[O-:53].[CH3:56][CH2:57][O:58][C:59]([CH3:60])=[O:61].[CH:21]1([NH:24][C:25]([c:26]2[cH:27][c:28]([F:42])[c:29]([CH3:41])[c:30]([B:32]3[O:33][C:34]([CH3:35])([CH3:36])[C:37]([CH3:38])([CH3:39])[O:40]3)[cH:31]2)=[O:43])[CH2:22][CH2:23]1.[Na+:54].[Na+:55].[O:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1.[cH:62]1[cH:63][cH:64][c:65]([P:66]([Pd:67]([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([P:87]([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[P:106]([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)([c:125]2[cH:126][cH:127][cH:128][cH:129][cH:130]2)[c:131]2[cH:132][cH:133][cH:134][cH:135][cH:136]2)[cH:137][cH:138]1>>[c:2]1(-[c:30]2[c:29]([CH3:41])[c:28]([F:42])[cH:27][c:26]([C:25]([NH:24][CH:21]3[CH2:22][CH2:23]3)=[O:43])[cH:31]2)[cH:3][c:4]2[c:5]([n:6]([CH3:9])[c:7]1=[O:8])[n:10](-[c:13]1[c:14]([F:20])[cH:15][cH:16][cH:17][c:18]1[F:19])[n:11][cH:12]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a0adc226bc314644a9b472dab1b67c93
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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