Dichloromethane → 4-(4-Aminophenylthio)-3-(6-fluoro-7-isopropylpyrido[2,3-d]pyrimidin-4-ylamino)benzoic acid
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][c:9]1[cH:10][cH:11][c:12]([S:15][c:16]2[c:17]([NH:25][c:26]3[c:27]4[c:28]([n:29][cH:30][n:31]3)[n:32][c:33]([CH:37]([CH3:38])[CH3:39])[c:34]([F:36])[cH:35]4)[cH:18][c:19]([C:20](=[O:21])[OH:22])[cH:23][cH:24]2)[cH:13][cH:14]1)([CH3:5])([CH3:6])[CH3:7].[Cl:47][CH2:48][Cl:49].[OH:40][C:41]([C:42]([F:43])([F:44])[F:45])=[O:46]>>[NH2:8][c:9]1[cH:10][cH:11][c:12]([S:15][c:16]2[c:17]([NH:25][c:26]3[c:27]4[c:28]([n:29][cH:30][n:31]3)[n:32][c:33]([CH:37]([CH3:38])[CH3:39])[c:34]([F:36])[cH:35]4)[cH:18][c:19]([C:20](=[O:21])[OH:22])[cH:23][cH:24]2)[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-a8ec871c5c4c4edd95835b582082f677
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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