Water → 4,6-Di-t-butyl-2-hydroxymethyl-2-methyl-5-trimethylsilyloxy-2,3-dihydrobenzofuran

HRID 1217642Notes

Reaction equation

HRID 1217642 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[c:6]([OH:21])[c:7]([C:17]([CH3:18])([CH3:19])[CH3:20])[cH:8][c:9]2[c:10]1[CH2:11][C:12]([CH3:14])([CH2:15][OH:16])[O:13]2.[Cl:35][CH2:36][Cl:37].[F:22][C:23]([F:24])([F:25])[S:26]([O:27][Si:28]([CH3:29])([CH3:30])[CH3:31])(=[O:32])=[O:33].[OH2:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[c:6]([O:21][Si:28]([CH3:29])([CH3:30])[CH3:31])[c:7]([C:17]([CH3:18])([CH3:19])[CH3:20])[cH:8][c:9]2[c:10]1[CH2:11][C:12]([CH3:14])([CH2:15][OH:16])[O:13]2

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 65367Trimethylsilyl triflateHCID 15485720HCID 15485720, compound

Product 1

HCID 232880414,6-Di-t-butyl-2-hydroxymethyl-2-methyl-5-trimethylsilyloxy-2,3-dihydrobenzofuran

Sources & evidence

ORD record
ord-7152be30e6bf4ce99f224472f3ab3b9f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…