Bicarbonate Ion → Methyl 2-amino-5-[5-[[2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl]-methylamino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]pent-4-ynoate
Reaction equation
[Cl:59][CH2:60][Cl:61].[F:8][C:9]([c:10]1[cH:11][c:12]([C:20]([C:21](=[O:22])[N:23]([c:24]2[c:25](-[c:46]3[c:47]([CH3:53])[cH:48][c:49]([F:52])[cH:50][cH:51]3)[cH:26][c:27]([C:30]#[C:31][CH2:32][CH:33]([C:34](=[O:35])[O:36][CH3:37])[NH:38][C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])[n:28][cH:29]2)[CH3:54])([CH3:55])[CH3:56])[cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]1)([F:57])[F:58].[Na+:66].[O-:62][C:63]([OH:64])=[O:65].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[F:8][C:9]([c:10]1[cH:11][c:12]([C:20]([C:21](=[O:22])[N:23]([c:24]2[c:25](-[c:46]3[c:47]([CH3:53])[cH:48][c:49]([F:52])[cH:50][cH:51]3)[cH:26][c:27]([C:30]#[C:31][CH2:32][CH:33]([C:34](=[O:35])[O:36][CH3:37])[NH2:38])[n:28][cH:29]2)[CH3:54])([CH3:55])[CH3:56])[cH:13][c:14]([C:16]([F:17])([F:18])[F:19])[cH:15]1)([F:57])[F:58]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e6e2b7c9ee7a4862929803faca0796e6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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