Water → 1-Cbz-3-Boc-Amino pyrrolidine

HRID 1217793Notes

Reaction equation

HRID 1217793 reaction equation
[Cl:14][C:15](=[O:16])[O:17][CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1.[Cl:25][CH2:26][Cl:27].[NH:1]1[CH2:2][CH:3]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:4][CH2:5]1.[OH2:28]>>[N:1]1([C:15](=[O:16])[O:17][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[CH2:2][CH:3]([NH:6][C:7]([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:13])[CH2:4][CH2:5]1

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 10387Benzyl chloroformateHCID 2757234tert-butyl N-(pyrrolidin-3-yl)carbamate

Product 1

HCID 145554781-Cbz-3-Boc-Amino pyrrolidine

Sources & evidence

ORD record
ord-b70a08ee432f4d02aa070c5f100c20f8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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