Methyl iodide → N-(4-chloro-3-methyl-5-isoxazolyl)-3-sulfamoyl-5-methyl-2-thiophenecarboxylic acid

HRID 1217906Notes

Reaction equation

HRID 1217906 reaction equation
[CH3:20][CH2:21][CH2:22][CH2:23][Li:24].[Cl:1][c:2]1[c:3]([CH3:19])[n:4][o:5][c:6]1[NH:7][S:8](=[O:9])(=[O:10])[c:11]1[c:12]([C:16](=[O:17])[OH:18])[s:13][cH:14][cH:15]1.[I:25][CH3:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[Cl:1][c:2]1[c:3]([CH3:19])[n:4][o:5][c:6]1[NH:7][S:8](=[O:9])(=[O:10])[c:11]1[c:12]([C:16](=[O:17])[OH:18])[s:13][c:14]([CH3:20])[cH:15]1

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 108058203-(N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl)thiophene-2-carboxylic acidHCID 178418339Butyllithium

Product 1

HCID 11782667N-(4-chloro-3-methyl-5-isoxazolyl)-3-sulfamoyl-5-methyl-2-thiophenecarboxylic acid

Sources & evidence

ORD record
ord-1208988b35d84e69998afdeba89793c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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