Water → [1-(3-Amino-1-cyclopropyl-6-fluoro-2,4-dioxo-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidin-7-yl)pyrrolidin-3-yl]carbamic acid tert-butyl ester

HRID 1218051노트

반응식

[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24]([NH:25][CH:26]1[CH2:27][NH:28][CH2:29][CH2:30]1)=[O:31].[CH3:41][C:42]#[N:43].[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[NH2:1][n:2]1[c:3](=[O:18])[n:4]([CH:15]2[CH2:16][CH2:17]2)[c:5]2[c:6]([c:7]1=[O:8])[cH:9][c:10]([F:14])[c:11]([Cl:13])[n:12]2.[OH2:44]>>[NH2:1][n:2]1[c:3](=[O:18])[n:4]([CH:15]2[CH2:16][CH2:17]2)[c:5]2[c:6]([c:7]1=[O:8])[cH:9][c:10]([F:14])[c:11]([N:28]1[CH2:27][CH:26]([NH:25][C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:31])[CH2:30][CH2:29]1)[n:12]2