Pyridine → [1-[[5-Tert-butyl-2-(5-cyano-2-methoxybenzoyl)imino-1,3-thiazol-3-yl]methyl]cyclobutyl] acetate

HRID 1218417Notes

Reaction equation

HRID 1218417 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][n:7]([CH2:23][C:24]2([OH:28])[CH2:25][CH2:26][CH2:27]2)[c:8](=[N:10][C:11]([c:12]2[c:13]([O:20][CH3:21])[cH:14][cH:15][c:16]([C:18]#[N:19])[cH:17]2)=[O:22])[s:9]1.[CH3:29][C:30](=[O:31])[O:32][C:33](=[O:34])[CH3:35].[CH3:36][N:37]([CH3:38])[c:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1.[cH:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][n:7]([CH2:23][C:24]2([O:28][C:30]([CH3:29])=[O:31])[CH2:25][CH2:26][CH2:27]2)[c:8](=[N:10][C:11]([c:12]2[c:13]([O:20][CH3:21])[cH:14][cH:15][c:16]([C:18]#[N:19])[cH:17]2)=[O:22])[s:9]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 142844-(Dimethylamino)pyridineHCID 66852270N-[5-tert-butyl-3-[(1-hydroxycyclobutyl)methyl]-1,3-thiazol-2-ylidene]-5-cyano-2-methoxybenzamide

Product 1

HCID 66852492[1-[[5-Tert-butyl-2-(5-cyano-2-methoxybenzoyl)imino-1,3-thiazol-3-yl]methyl]cyclobutyl] acetate

Sources & evidence

ORD record
ord-c87bace773c0471f880c78cfd1078fda
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…