1,2-Dichloroethane → (+/-)-6-[4-(3-Benzyl-piperidin-1-ylmethyl)-phenoxy]-nicotinamide
Reaction equation
[C:32]([O:33][BH-:34]([O:35][C:36](=[O:37])[CH3:38])[O:39][C:40](=[O:41])[CH3:42])(=[O:43])[CH3:44].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[CH2:9][NH:10][CH2:11][CH2:12][CH2:13]1.[CH2:56]([Cl:57])[Cl:58].[CH3:46][C:47](=[O:48])[OH:49].[CH3:54][OH:55].[CH:14](=[O:15])[c:16]1[cH:17][cH:18][c:19]([O:20][c:21]2[n:22][cH:23][c:24]([C:25](=[O:26])[NH2:27])[cH:28][cH:29]2)[cH:30][cH:31]1.[Cl:50][CH2:51][CH2:52][Cl:53].[Na+:45]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[CH2:9][N:10]([CH2:14][c:16]2[cH:17][cH:18][c:19]([O:20][c:21]3[n:22][cH:23][c:24]([C:25](=[O:26])[NH2:27])[cH:28][cH:29]3)[cH:30][cH:31]2)[CH2:11][CH2:12][CH2:13]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-2fc9a56b80b34c0baab53c17fdbddd5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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