Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1218694Generated: October 31, 2026

Methanol → Tert-butyl 5-[2-amino-3-(3,5-difluorophenyl)-1-hydroxypropyl]-2-(2,2-dimethylpropoxy)morpholine-4-carboxylate

https://huagongshe.com/reaction/1218694

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantNickel DichlorideHCID 24385—
ReactantBorohydrideHCID 28123—
ReactantTert-butyl 5-[3-(3,5-difluorophenyl)-1-hydroxy-2-nitropropyl]-2-(2,2-dimethylpropoxy)morpholine-4-carboxylateHCID 77514573—
ProductTert-butyl 5-[2-amino-3-(3,5-difluorophenyl)-1-hydroxypropyl]-2-(2,2-dimethylpropoxy)morpholine-4-carboxylateHCID 77514319—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-4154c6cd35204eea9b565bd10a903eb7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)