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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1218841Generated: November 1, 2026

Toluene → 2-(4'-bromo-5,6-difluoro-2'-oxospiro[1-benzofuran-3,3'-indol]-1'(2' H)-yl)-N-(2-fluorophenyl)acetamide

https://huagongshe.com/reaction/1218841

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
Reactant2-FluoroanilineHCID 9584—
ReactantOxalyl chlorideHCID 65578—
Reactant(4'-bromo-5,6-difluoro-2'-oxospiro[1-benzofuran-3,3'-indol]-1'(2'H)-yl)acetic acidHCID 66641960—
Product2-(4'-bromo-5,6-difluoro-2'-oxospiro[1-benzofuran-3,3'-indol]-1'(2' H)-yl)-N-(2-fluorophenyl)acetamideHCID 59263509—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-e48e89f10a76453fa0d7eb3a0fc7485d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)