Toluene → 2-(4'-bromo-5,6-difluoro-2'-oxospiro[1-benzofuran-3,3'-indol]-1'(2' H)-yl)-N-(2-fluorophenyl)acetamide
Reaction equation
[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH2:22][C:23](=[O:24])[OH:25])[C:9](=[O:21])[C:10]21[CH2:11][O:12][c:13]2[c:14]1[cH:15][c:16]([F:20])[c:17]([F:19])[cH:18]2.[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[Cl:26][C:27]([C:28]([Cl:29])=[O:30])=[O:31].[Cl:52][CH2:53][Cl:54].[NH2:37][c:38]1[cH:39][cH:40][cH:41][cH:42][c:43]1[F:44].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH2:22][C:23](=[O:25])[NH:37][c:38]1[cH:39][cH:40][cH:41][cH:42][c:43]1[F:44])[C:9](=[O:21])[C:10]21[CH2:11][O:12][c:13]2[c:14]1[cH:15][c:16]([F:20])[c:17]([F:19])[cH:18]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-e48e89f10a76453fa0d7eb3a0fc7485d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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