Pyridine → 2-(2'-tert-Butylsulfamoyl-3-fluoro-biphenyl-4-ylcarbamoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:13](=[O:14])[OH:15])[CH2:10][CH2:11][CH2:12]1.[C:28]([CH3:29])([CH3:30])([CH3:31])[NH:32][S:33](=[O:34])(=[O:35])[c:36]1[c:37](-[c:42]2[cH:43][c:44]([F:49])[c:45]([NH2:48])[cH:46][cH:47]2)[cH:38][cH:39][cH:40][cH:41]1.[CH3:50][CH2:51][O:52][CH2:53][CH3:54].[Cl:22][C:23]([C:24]([Cl:25])=[O:26])=[O:27].[Cl:55][CH2:56][Cl:57].[cH:16]1[cH:17][cH:18][n:19][cH:20][cH:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:13](=[O:15])[NH:48][c:45]2[c:44]([F:49])[cH:43][c:42](-[c:37]3[c:36]([S:33]([NH:32][C:28]([CH3:29])([CH3:30])[CH3:31])(=[O:34])=[O:35])[cH:41][cH:40][cH:39][cH:38]3)[cH:47][cH:46]2)[CH2:10][CH2:11][CH2:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b9a419595b124ba489cbd9631583f54f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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