Hydrochloric Acid → 1-(2,4-Difluorophenyl)-6-fluoro-3-hydroxy-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dione

HRID 1219567Notes

Reaction equation

HRID 1219567 reaction equation
[ClH:29].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:28])[n:11]([OH:27])[c:12](=[O:26])[c:13]3[cH:14][c:15]([F:25])[c:16]([N:19]4[CH2:20][CH:21]([NH2:24])[CH2:22][CH2:23]4)[cH:17][c:18]23)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:28])[n:11]([OH:27])[c:12](=[O:26])[c:13]3[cH:14][c:15]([F:25])[c:16]([N:19]4[CH2:20][CH2:21][CH2:22][CH2:23]4)[cH:17][c:18]23)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178999547-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-3-hydroxyquinazoline-2,4-dione

Product 1

HCID 226329611-(2,4-Difluorophenyl)-6-fluoro-3-hydroxy-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dione

Sources & evidence

ORD record
ord-c86aa61f036e4cf5b8974b50c767ca72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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