Tetrahydrofuran → Oxalic Acid

HRID 1219958Notes

Reaction equation

HRID 1219958 reaction equation
[C:40]([C:41](=[O:42])[O-:43])(=[O:44])[O-:45].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:17][c:18]3[cH:19][cH:20][c:21]([O:24][CH2:25][CH2:26][N:27]4[CH2:28][CH2:29][CH2:30][CH2:31]4)[cH:22][cH:23]3)[c:10]3[c:11]([s:12]2)[cH:13][cH:14][cH:15][cH:16]3)[cH:6][cH:7]1.[OH:32][CH2:33][CH:34]1[CH2:35][CH2:36][C:37](=[O:39])[NH:38]1>>[C:40]([C:41](=[O:42])[OH:43])(=[O:44])[OH:45].[O:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH2:17][c:18]3[cH:19][cH:20][c:21]([O:24][CH2:25][CH2:26][N:27]4[CH2:28][CH2:29][CH2:30][CH2:31]4)[cH:22][cH:23]3)[c:10]3[c:11]([s:12]2)[cH:13][cH:14][cH:15][cH:16]3)[cH:6][cH:7]1)[CH2:33][CH:34]1[CH2:35][CH2:36][C:37](=[O:39])[NH:38]1

Participants

6

Reactant 4

HCID 8028TetrahydrofuranHCID 71081OxalateHCID 5583595-(Hydroxymethyl)pyrrolidin-2-oneHCID 224626554-[3-[4-[2-(1-Pyrrolidinyl)ethoxy]benzyl]benzo[b]thiophen-2-yl]phenol

Product 2

HCID 971Oxalic AcidHCID 213366415-[[4-[3-[[4-(2-Pyrrolidin-1-ylethoxy)phenyl]methyl]-1-benzothiophen-2-yl]phenoxy]methyl]pyrrolidin-2-one

Sources & evidence

ORD record
ord-110e7bbcb7e240f99d141f7999f662d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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