Dichloromethane → 3-(3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)phenylamino)propanoic acid
Reaction equation
[Cl:43][CH2:44][Cl:45].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[F:8][c:9]1[cH:10][c:11]([NH:33][CH2:34][CH2:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[cH:12][cH:13][c:14]1-[c:15]1[s:16][c:17]2[n:18][c:19]([C:24]3([c:27]4[cH:28][cH:29][cH:30][cH:31][cH:32]4)[CH2:25][CH2:26]3)[cH:20][cH:21][c:22]2[n:23]1>>[F:8][c:9]1[cH:10][c:11]([NH:33][CH2:34][CH2:35][C:36](=[O:37])[OH:38])[cH:12][cH:13][c:14]1-[c:15]1[s:16][c:17]2[n:18][c:19]([C:24]3([c:27]4[cH:28][cH:29][cH:30][cH:31][cH:32]4)[CH2:25][CH2:26]3)[cH:20][cH:21][c:22]2[n:23]1Participants
4
Sources & evidence
- ORD record
- ord-a1176111f9114926af42346c06398048
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…