Dimethylformamide → 4-[2-(2,4-Bis-benzyloxy-5-chloro-phenyl)-2-oxo-ethyl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[C:34]([CH3:35])([CH3:36])([CH3:37])[O:38][C:39](=[O:40])[N:41]1[CH2:42][CH2:43][NH:44][CH2:45][CH2:46]1.[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][c:15]1[c:16]([C:30]([CH2:31][Br:32])=[O:33])[cH:17][c:18]([Cl:29])[c:19]([O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:20]1.[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[Cs+:5].[Cs+:6]>>[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][c:15]1[c:16]([C:30]([CH2:31][N:44]2[CH2:43][CH2:42][N:41]([C:39]([O:38][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:40])[CH2:46][CH2:45]2)=[O:33])[cH:17][c:18]([Cl:29])[c:19]([O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:20]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e2aa3562632e4bbfbfd2c6efba8d0d68
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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