Tetrahydrofuran → 1,2,3,4-Tetrahydronaphthalen-1-yl 2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

HRID 1220212노트

반응식

[CH3:31][c:32]1[cH:33][c:34]([C:54]([F:55])([F:56])[F:57])[n:35][n:36]1[CH2:37][C:38](=[O:39])[N:40]1[CH2:41][CH2:42][CH:43]([c:46]2[s:47][cH:48][c:49]([C:51](=[O:52])[OH:53])[n:50]2)[CH2:44][CH2:45]1.[CH:1]1([OH:11])[CH2:2][CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[O:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1.[c:12]1([P:13]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:26][cH:27][cH:28][cH:29][cH:30]1>>[CH:1]1([O:11][C:51]([c:49]2[cH:48][s:47][c:46]([CH:43]3[CH2:42][CH2:41][N:40]([C:38]([CH2:37][n:36]4[c:32]([CH3:31])[cH:33][c:34]([C:54]([F:55])([F:56])[F:57])[n:35]4)=[O:39])[CH2:45][CH2:44]3)[n:50]2)=[O:52])[CH2:2][CH2:3][CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21