Dimethyl Sulfoxide → (+/-)-6-[2-Chloro-4-(3-phenyl-pyrrolidin-1-ylmethyl)-phenoxy]-nicotinamide
Reaction equation
[C:29]([O-:30])(=[O:31])[O-:32].[CH3:37][S:38]([CH3:39])=[O:40].[Cl:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([C:9]#[N:10])[cH:11][cH:12]2)[cH:13][cH:14][c:15]([CH2:17][N:18]2[CH2:19][CH:20]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:21][CH2:22]2)[cH:16]1.[K+:33].[K+:34].[OH:35][OH:36]>>[Cl:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][c:8]([C:9]([NH2:10])=[O:30])[cH:11][cH:12]2)[cH:13][cH:14][c:15]([CH2:17][N:18]2[CH2:19][CH:20]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:21][CH2:22]2)[cH:16]1Participants
6
Sources & evidence
- ORD record
- ord-3c0271740c514052b9ea380217de9ebb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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