Dimethylformamide → 2-Bromo-5-[chloro(2,3,6-trifluorophenyl)methyl]-4-methylpyridine

HRID 1220259Notes

Reaction equation

HRID 1220259 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:19])[c:5]([CH:8]([OH:9])[c:10]2[c:11]([F:18])[c:12]([F:17])[cH:13][cH:14][c:15]2[F:16])[cH:6][n:7]1.[CH2:29]([Cl:30])[Cl:31].[CH3:24][N:25]([CH3:26])[CH:27]=[O:28].[S:20]([Cl:21])([Cl:22])=[O:23]>>[Br:1][c:2]1[cH:3][c:4]([CH3:19])[c:5]([CH:8]([c:10]2[c:11]([F:18])[c:12]([F:17])[cH:13][cH:14][c:15]2[F:16])[Cl:22])[cH:6][n:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 86631150(6-Bromo-4-methylpyridin-3-yl)(2,3,6-trifluorophenyl)methanol

Product 1

HCID 866311512-Bromo-5-[chloro(2,3,6-trifluorophenyl)methyl]-4-methylpyridine

Sources & evidence

ORD record
ord-cf22159b03704afcb37b5532997df99b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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