Tetrahydrofuran → HCID 59242077, compound

HRID 1220314Notes

Reaction equation

[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[Cl:13][CH2:14][c:15]1[n:16][c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[c:23]([N:25]([CH3:26])[c:27]2[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)[n:24]1.[NH:1]1[C:2](=[O:7])[CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH2:14][c:15]2[n:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[c:23]([N:25]([CH3:26])[c:27]3[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]3)[n:24]2)[C:2](=[O:7])[CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 126652-Piperidone

HCID 11358914(2-Chloromethyl-quinazolin-4-yl)-(4-methoxy-phenyl)-methyl-amine

HCID 178418339Butyllithium

Product 1

HCID 59242077HCID 59242077, compound

Sources & evidence

ORD record: ord-c927b684d51248aea4e79621d5d8f80f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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