Bromide ion → 5-Ethyl-6-methoxy-2-methyl-nicotinic acid methyl ester
Reaction equation
[Br-:12].[Br:18][c:19]1[c:20]([CH3:29])[n:21][c:22]([O:27][CH3:28])[c:23]([CH2:25][CH3:26])[cH:24]1.[CH2:13]([Mg+:14])[CH2:15][CH2:16][CH3:17].[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:30][O:31][C:32](=[O:33])[O:34][CH3:35].[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[CH3:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[c:19]1([C:32]([O:31][CH3:30])=[O:33])[c:20]([CH3:29])[n:21][c:22]([O:27][CH3:28])[c:23]([CH2:25][CH3:26])[cH:24]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-a66d1ba76f6649d6b1ae8fc9ecc94b87
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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