HRID1220556

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID887

Methanol

CH4O

HCID923

Sodium ion

Na+

HCID8028

Tetrahydrofuran

C4H8O

HCID28123

Tetrahydroborate

H4B-

HCID81531

Diisopropylethylamine

C8H19N

HCID2760133

4-(tert-Butoxycarbonyl)morpholine-3-carboxylic acid

C10H17NO5

HCID5058359

Tert-butyl 3-(hydroxymethyl)morpholine-4-carboxylate

C10H19NO4

HCID6992154

未命名化合物

结构：C=CCOC1CC(C2OC(=O)NC2Cc2cc(F)cc(F)c2)N(C(c2ccccc2)c2ccccc2)C1

HCID178458213

未命名化合物

PRODUCTS

生成物

结构：O=C1NC(Cc2cc(F)cc(F)c2)C(C2CC(O)CN2C(c2ccccc2)c2ccccc2)O1

HCID178517678

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-39f143291bc6464899df97801413ecd0
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (5/10)

反应 SMILES

[BH4-:84].[C:53]([O:54][C:55]([N:56]1[CH2:57][CH2:58][O:59][CH2:60][CH:61]1[C:62]([OH:63])=[O:64])=[O:65])([CH3:66])([CH3:67])[CH3:68].[CH2:86]1[O:87][CH2:88][CH2:89][CH2:90]1.[CH3:91][OH:92].[CH:69]([N:70]([CH2:71][CH3:72])[CH:73]([CH3:74])[CH3:75])([CH3:76])[CH3:77].[Cl:78][CH2:79][CH2:80][C:81]([O-:82])=[O:83].[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[NH:7][C:8](=[O:33])[O:9][CH:10]2[CH:11]2[N:12]([CH:20]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:13][CH:14]([O:16][CH2:17][CH:18]=[CH2:19])[CH2:15]2)[cH:34][c:35]([F:37])[cH:36]1.[Na+:85].[OH:38][CH2:39][CH:40]1[N:41]([C:42]([O:43][C:44]([CH3:45])([CH3:46])[CH3:47])=[O:48])[CH2:49][CH2:50][O:51][CH2:52]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[NH:7][C:8](=[O:33])[O:9][CH:10]2[CH:11]2[N:12]([CH:20]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:13][CH:14]([OH:16])[CH2:15]2)[cH:34][c:35]([F:37])[cH:36]1