Formic Acid → N-(3-chloro-2-fluorophenyl)-7-methoxy-6-[(1-methylpyrrolidin-2-yl)methoxy]quinazolin-4-amine
Reaction equation
[CH2:33]=[O:34].[CH2:35]([O:36][CH2:37][CH3:38])[CH3:39].[CH:30]([OH:31])=[O:32].[Cl:2][c:3]1[c:4]([F:29])[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:24][CH3:25])[c:14]([O:17][CH2:18][CH:19]4[NH:20][CH2:21][CH2:22][CH2:23]4)[cH:15][c:16]23)[cH:26][cH:27][cH:28]1.[ClH:1]>>[Cl:2][c:3]1[c:4]([F:29])[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:24][CH3:25])[c:14]([O:17][CH2:18][CH:19]4[N:20]([CH3:30])[CH2:21][CH2:22][CH2:23]4)[cH:15][c:16]23)[cH:26][cH:27][cH:28]1Participants
6
Sources & evidence
- ORD record
- ord-312af6218eef4e06ba4fa17fd653ca07
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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