Dimethylamine → 2-Dimethylamino-N-(3-{4-[3-methyl-4-(pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-prop-2-ynyl)-acetamide
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:34][NH:35][CH3:36].[CH3:42][OH:43].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][CH2:6][C:7]#[C:8][c:9]1[cH:10][c:11]2[c:12]([NH:19][c:20]3[cH:21][c:22]([CH3:33])[c:23]([O:26][c:27]4[cH:28][n:29][cH:30][cH:31][cH:32]4)[cH:24][cH:25]3)[n:13][cH:14][n:15][c:16]2[cH:17][cH:18]1>>[CH2:2]([C:3](=[O:4])[NH:5][CH2:6][C:7]#[C:8][c:9]1[cH:10][c:11]2[c:12]([NH:19][c:20]3[cH:21][c:22]([CH3:33])[c:23]([O:26][c:27]4[cH:28][n:29][cH:30][cH:31][cH:32]4)[cH:24][cH:25]3)[n:13][cH:14][n:15][c:16]2[cH:17][cH:18]1)[N:35]([CH3:34])[CH3:36]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2e90610cbc814a91a2d65c827c1407f3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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