Toluene → 2-Benzyloxycarbonylamino-3-{2,5-dimethoxy-6-[4-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-piperidin-1-yl]-pyrimidin-4-ylamino}-propionic acid
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:20][NH:21][c:22]1[n:23][c:24]([O:46][CH3:47])[n:25][c:26]([N:30]2[CH2:31][CH2:32][CH:33]([c:36]3[n:37][c:38]4[c:43]([cH:44][cH:45]3)[CH2:42][CH2:41][CH2:40][NH:39]4)[CH2:34][CH2:35]2)[c:27]1[O:28][CH3:29].[CH3:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1.[Cl:62][CH2:63][Cl:64].[OH:48][C:49]([C:50]([F:51])([F:52])[F:53])=[O:54]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([C:13](=[O:14])[OH:15])[CH2:20][NH:21][c:22]1[n:23][c:24]([O:46][CH3:47])[n:25][c:26]([N:30]2[CH2:31][CH2:32][CH:33]([c:36]3[n:37][c:38]4[c:43]([cH:44][cH:45]3)[CH2:42][CH2:41][CH2:40][NH:39]4)[CH2:34][CH2:35]2)[c:27]1[O:28][CH3:29]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-244945c006684d9fa089a3218a2cf50a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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