Hydrochloric Acid → 1-(2-(4-aminopiperidin-1-yl)ethyl)-1,7-naphthyridin-2(1H)-one

HRID 1221475Notes

Reaction equation

HRID 1221475 reaction equation
[CH2:28]([OH:29])[CH3:30].[CH3:32][CH2:33][OH:34].[ClH:31].[O:1]=[c:2]1[n:3]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([NH:20][C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:18][CH2:19]2)[c:4]2[cH:5][n:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1>>[O:1]=[c:2]1[n:3]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][CH:17]([NH2:20])[CH2:18][CH2:19]2)[c:4]2[cH:5][n:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702Ethanol2×HCID 57815235tert-butyl (1-(2-(2-oxo-1,7-naphthyridin-1(2H)-yl)ethyl)piperidin-4-yl)carbamate

Product 1

HCID 578152611-(2-(4-aminopiperidin-1-yl)ethyl)-1,7-naphthyridin-2(1H)-one

Sources & evidence

ORD record
ord-8fb3ad9b014a40f08630093171fea9b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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