Methanol → 1-O-tert-butyl 2-O-methyl 4-(7-bromo-6-methoxyisoquinolin-1-yl)oxypyrrolidine-1,2-dicarboxylate
Reaction equation
[Br:1][c:2]1[c:3]([O:28][CH3:29])[cH:4][c:5]2[cH:6][cH:7][n:8][c:9]([O:12][CH:13]3[CH2:14][CH:15]([C:25](=[O:26])[OH:27])[N:16]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:17]3)[c:10]2[cH:11]1.[CH3:37][OH:38].[Si:30]([CH3:31])([CH:32]=[N+:33]=[N-:34])([CH3:35])[CH3:36]>>[Br:1][c:2]1[c:3]([O:28][CH3:29])[cH:4][c:5]2[cH:6][cH:7][n:8][c:9]([O:12][CH:13]3[CH2:14][CH:15]([C:25](=[O:26])[O:27][CH3:31])[N:16]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:17]3)[c:10]2[cH:11]1Participants
4
Sources & evidence
- ORD record
- ord-b6473eb4048c4df7a0baf5c386610872
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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