4-Piperidinecarboxamide → 1-(2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

HRID 122165Notes

Reaction equation

HRID 122165 reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[Cl:1][c:2]1[n:3][c:4]([Cl:11])[c:5]2[c:6]([n:7]1)[nH:8][cH:9][cH:10]2.[NH:12]1[CH2:13][CH2:14][CH:15]([C:16](=[O:17])[NH2:18])[CH2:19][CH2:20]1.[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1>>[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][CH:15]([C:16](=[O:17])[NH2:18])[CH2:19][CH2:20]2)[c:5]2[c:6]([n:7]1)[nH:8][cH:9][cH:10]2

Participants

5

Reactant 4

HCID 37724-PiperidinecarboxamideHCID 8471TriethylamineHCID 312751,4-DioxaneHCID 141168712,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 579902901-(2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide

Sources & evidence

ORD record
ord-65c2c73dec034442ae2300cd02ab8a28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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