Acetonitrile → 6-(4-Fluoro-phenyl)-5-piperidin-1-yl-pyrazine-2-carboxylic acid methyl ester
Reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[CH3:25][C:26]#[N:27].[CH3:7][O:8][C:9](=[O:10])[c:11]1[n:12][c:13](-[c:18]2[cH:19][cH:20][c:21]([F:24])[cH:22][cH:23]2)[c:14]([Br:17])[n:15][cH:16]1>>[CH2:1]1[CH2:2][CH2:3][N:4]([c:14]2[c:13](-[c:18]3[cH:19][cH:20][c:21]([F:24])[cH:22][cH:23]3)[n:12][c:11]([C:9]([O:8][CH3:7])=[O:10])[cH:16][n:15]2)[CH2:5][CH2:6]1Participants
4
Sources & evidence
- ORD record
- ord-7827a32470a84631baa51246c8c4e013
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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